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Project title           The role of supervise exercise training that adjunctive to compression therapy in patients with chronic venous ulcer

Project Investigator         

Kanokwan Kulprachakarn, PhD.

Co Investigator    

Professor Kittipan Rerkasem, MD., PhD.

Mujalin Prasannarong, PhD.

Christine  Rojawat, MD.

Sakaewan Ounjaijean, PhD.

Ms. Orapin Pongtam

Research objective

The aim of this study was to elucidate the efficacy of calf muscle exercise adjunct with standard compression therapy in patients with chronic venous ulcer.

Funding agency                

Chiang Mai University

Study site                         

Maharaj Nakorn Chiang Mai hospital, Chiang Mai University, Thailand

Study design

We hypothesized that calf muscle exercise addition to standard compression therapy could help reduce venous ulcer size and accelerate wound healing. A randomized control trial (RCT) study was conducted. Patients were randomized to supervised exercise and compression therapy or compression therapy alone. Both groups were assessed for ulcer healing, inflammation, ankle joint range of motion, calf muscle strength, and calf muscle endurance, respectively.

Study period

October 2016 – September 2017

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