|Current event plus at least one previous
episode in past six months.
This is a 3-year-old
child with recurrent oral ulcerations. Angular cheilitis presents
as erythema or fissuring of the corners of the mouth.
Oral ulcerations were diagnosed as
1. herpes simplex ulcerations,
2. recurrent aphthous ulcers (RAU),
and 3. atypical ulceration.
RAU were diagnosed according to their clinical presentation on
oral mucosa. History of RAU was also contributory.
and large persistent ulcerations are presented in the oral cavity.
Atypical ulceration (formerly described as ulceration nonspecified)
presented as large persistent ulcerations (with yellow-grey pseudomembrane)
particularly located on the fauces.
This type of ulcer is now generally considered
to represent major aphthous ulcerations. Some of these are extremely
resistant to therapy in HIV-infected patients.
||This condition is one of the
most common oral manifestations seen in HIV-infected children around
the world [ref 1, 2].
1. Coogan MM, Greenspan J, Challacombe SJ. Oral lesions in infection
with human immunodeficiency virus. Bulletin of the World Health
2. Reichart PA, Khongkhunthian P, Bendick C. Oral manifestations
in HIV-infected individuals from Thailand and Cambodia. Med Microbiol