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Herpes
zoster |
Painful rash with fluid-filled blisters, dermatomal distribution, can be haemorrhagic on erythematous background, and may become large and confluent. Usually It does not cross the midline. |
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A 2-year-old HIV-infected
child with herpes zoster (A, B) |
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Over a period
of 4-7 days, lesions form bullae and crusts and begin to heal. |
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Herpes zoster in an HIV-infected child tends to be more severe, more painful, more hemorrhagic and the incidence of disseminated form, permanent scarring and recurrence seems to be higher than in a healthy child. |
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Treatment of severe cases consists of intravenous acyclovir. |
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A 9-year-old HIV-infected child with herpes zoster which crosses the midline. |
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A 11-year-old HIV-infected child with disseminated herpes zoster. |
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Light microscopy using the Tzanck smear (scraping epidermal cells from an ulcer based and stained with Wright-Giemsa stain) showing multinucleated giant cells and intranuclear inclusions. |
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