Oral hairy leukoplakia
Fine small linear patches on lateral borders of tongue, generally bilaterally, which do not scrape off.

OHL is less commonly seen in children than adults. The frequency of occurrence of OHL increases as the immunity of the patients decreases. It presents as a corrugated or "hairy" white lesion on the lateral surface of the tongue that is not removed by gentle scraping. OHL is usually asymptomatic, but large lesions may impair taste and decrease appetite. The diagnosis of OHL is generally based on the typical appearance of the lesions in the appropriate clinical setting. Lesions temporarily respond to high-dose acyclovir or ganciclovir, podophyllin, and isotretinoin. It usually regresses with the institution of highly active antiretroviral therapy.


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